From text to tables: using large language
models-generated structured outputs to answer
scientific questions
Johannes Elias, Berlin, Germany
15:55 - 16:20
The 21st century biochemist: how practical AI
applications improve and simplify laboratory work
Mario Štefanović, Zagreb, Croatia
16:20 - 16:45
Large language models-based clinical decision support
William van Doorn, Maastricht, Netherlands
16:45 - 17:00
COFFEE BREAK
17:00 - 17:25
False discovery rate corrections in routine
laboratory diagnostics and biomarker discovery
Ivana Marković, Osijek, Croatia
17:25 - 17:50
Deep learning-based classification of urinary
sediment particles
Glynis Frans, Leuven, Belgium
17:50 - 18:15
Single-cell analysis via machine and statistical
learning of mass spectrometry images
Željko Debeljak, Osijek, Croatia
BREAK
19:00 - 19:30
OPENING CEREMONY · Orlando A+B
19:30 - 20:15
Honorary Lecture
Biochemistry and the Philosophy of Man
Orlando A+B
19:30 - 20:15
Stribor Marković, Rijeka, Croatia
9:00 - 9:45
Plenary Lecture
Research vs. clinical laboratory methods and
regulations: understanding the key differences
Orlando A+B
Chair:
Ivana Ćelap
9:00 - 9:45
Tomáš Zima, Prague, Czech Republic
9:45 - 10:00
COFFEE BREAK
10:00 - 12:00 · PARALLEL PROGRAM
Symposium
Life-threatening bleeding: diagnosis and
contemporary management
Orlando A
Chair:
Marija Milić
10:00 - 10:25
Laboratory diagnosis in massive hemorrhage
Slavica Kvolik, Osijek, Croatia
10:25 - 10:50
The role of viscoelastic testing in assessing
hemostasis
Marija Milić, Osijek, Croatia
10:50 - 11:15
Challenges in the laboratory diagnosis of
acquired hemophilia
Désirée Coen Herak, Zagreb, Croatia
11:15 - 11:40
Updated definition and scoring of disseminated
intravascular coagulation in 2025
Jecko Thachil, Manchester, United Kingdom
11:40 - 12:00
Discussion
Symposium
Modern approach to therapeutic drug monitoring
(TDM)
Orlando B
Chair:
Mila Lovrić
10:00 - 10:25
Different faces of therapeutic drug monitoring
Mila Lovrić, Zagreb, Croatia
10:25 - 10:50
Clinical use of therapeutic drug monitoring for
psychoactive drugs - from retrospective problem
solving to clinical decision support
Tore Haselmo, Oslo, Norway
10:50 - 11:15
Clinical application of therapeutic monitoring
of immunosuppressants - is there place for
improvement?
Matea Ivić, Zagreb, Croatia
11:15 - 11:40
Complementary use of TDM and PGx - focus on
drugs for which we lack TDM
Lana Ganoci, Zagreb, Croatia
11:40 - 12:00
Discussion
12:00 - 12:45
Educational Workshop
Digital transformation of laboratory medicine
Orlando A
12:00 - 12:45
Ana Ćuk, Mostar, Bosnia and Herzegovina
12:00 - 12:30
Educational Workshop
Serum vs. plasma: Separating Evidence from Assumption
Orlando B
12:00 - 12:30
Brendan Meyer, EMEA Becton Dickinson Medical
Essentials, Specimen Management
12:45 - 13:15
Educational Workshop
Validated, Acessible, Actionable: Blood-based biomarkers in neurology in routine patient care
Orlando B
12:45 - 13:15
Valentina Vidranski, Zagreb, Croatia
13:15 - 14:00
LUNCH BREAK
14:00 - 15:00
Oral Poster Presentations
Orlando A
Chair:
Jasenka Wagner Kostadinović
Impact of CYP2C19, CYP2B6, ABCB1 and 5-HTTLPR
pharmacogenetic variants on sertraline
pharmacokinetics, therapeutic response and adverse
drug reactions in the treatment of depression /
Lana Ganoci
Is measuring carbamazepine concentration sufficient
for therapeutic drug monitoring in patients receiving
carbamazepine therapy: a pilot study /
Nora Nikolac Gabaj
Area under the curve (AUC): A valuable indicator of
mycophenolic acid dosing success / Sven Komljenović
Integrated genomic profiling of ovarian cancer
reveals low tumor mutational burden, microsatellite
stability, and actionable alterations / Tadej Pajič
Clinical validation of digital PCR-based ESR1 mutation
detection in circulating cell-free tumor DNA from
patients with breast cancer / Marina Tomičević
Bence Jones protein in serum detected using
immunosubtraction electrophoresis / Dragana Šegulja
Indirect reference intervals for vitamin D using
Refine R / Sonja Homar
Indirect estimation of selenium reference intervals:
comparison of CLSI C28-A3 and RefineR approaches /
Nora Nikolac Gabaj
Implementation of the clinical decision support
algorithm for screening of hemoglobinopathies:
preliminary results from the University Hospital
Centre Zagreb / Ivana Lapić
15:00 - 16:00
Educational Workshop
Innovating patient care: Blood-based biomarkers
for neurodegenerative diseases
Orlando B
15:00 - 16:00
Jean-Sebastien Blanchet,
Beckman Coulter - EMEA
16:00 - 16:30
Educational Workshop
Redefining cancer genomics: Illumina roadmap
for oncology research
Orlando A
16:00 - 16:30
Alberto González Medina, Illumina Inc.
16:30 - 16:45
COFFEE BREAK
16:45 - 17:45
Symposium of the Working Group for
Laboratory Haematology
Platelets: small players, big challenges
Orlando B
Chair:
Vanja Radišić Biljak
16:45 - 17:45
Ana Nikler, Ivana Lapić,
Branka Krešić, Valentina Vidranski
9:00 - 9:45
Plenary Lecture
Medical biochemist in the educational system
Orlando A+B
Chair:
Ivanka Mikulić
9:00 - 9:45
Lada Rumora, Zagreb, Croatia
9:45 - 10:00
COFFEE BREAK
10:00 - 12:00 · PARALLEL PROGRAM
Symposium
Allergic diseases - pandemics of the future
Orlando A
Chair:
Adrijana Dorotić
10:00 - 10:25
Laboratory diagnostics of allergies using
modern technologies
Gordana Fressl Juroš, Zagreb, Croatia
10:25 - 10:50
Exploring the latest innovations in laboratory
diagnostics of anaphylaxis: towards personalized
approaches and biomarker development
Urška Bidovec-Stojkovič, Golnik, Slovenia
10:50 - 11:15
The role of laboratory diagnostics in
identification, monitoring and treatment
of patients with allergies
Branko Pevec, Zagreb, Croatia
11:15 - 11:40
New diagnostic biomarkers in allergology:
the path towards personalized allergy diagnostics
Adrijana Dorotić, Zagreb, Croatia
11:40 - 12:00
Discussion
Symposium
Women in sports - a multidisciplinary challenge
Orlando B
Chair:
Vanja Radišić Biljak
10:00 - 10:25
Can a single hormone define sex:
fair play or illusion in sport?
Lana Ružić Švegl, Zagreb, Croatia
10:25 - 10:50
Female athlete ≠ male athlete: the impact
of the menstrual cycle on sports performance
Damir Pekas, Zagreb, Croatia
10:50 - 11:15
HEMSTER study: the role of medical biochemist
in sports medicine
Vanja Radišić Biljak, Zagreb, Croatia
11:15 - 11:40
Beyond "bikini" fitness: effective exercise
programming for women’s health
Nebojša Trajković, Niš, Serbia
11:40 - 12:00
Discussion
12:00 - 12:45
Educational Workshop
Phadia systems: the worldwide reference making
a measurable difference, to simplify patient
diagnosis in allergy
Orlando A
12:00 - 12:45
Felix Gastager, HVD Lifesciences
12:00 - 12:30
Educational Workshop
New insight into laboratory automation
Orlando B
12:00 - 12:30
Emmeran Hauser, Sysmex
12:45 - 13:15
Educational Workshop
Molecular diagnostics of allergies
Orlando B
12:45 - 13:15
Refika Didem Eler, Siemens Healthineers
12:45 - 13:15
Educational Workshop
WizardLab: Integrated LIS that understands
the laboratory and people who lead it
Orlando A
12:45 - 13:15
Džemal Tipura, Tarik Pekušić, WizardHealth
13:15 - 14:00
LUNCH BREAK
14:00 - 15:00
Oral Poster Presentations
Orlando A
Chair:
Ivanka Mikulić
Impact of Normalization on the Lupus Anticoagulant
Diagnostic Workflow / Branka Krešić
Verification of Low Dose Ristocetin Induced Platelet
Aggregation on the Thrombomate XRA analyzer /
Tomislav Hrgović
Investigating the stability of third party quality
controls across haematology analysers / Ana Bronić
Toward establishing updated national reference
intervals in Croatia: A pilot study by the Croatian
Chamber of Medical Biochemistry using alkaline
phosphatase as a model analyte / Adriana Bokulić
Reference intervals for hematological parameters
in the umbilical cord blood samples on Advia 2021i
hematological analyzer / Vladimira Rimac
Serum GFAP and UCH-L1 in relation to CT findings
in Traumatic Brain Injury / Ante Pušić
Impact of menstrual cycle phase on CA125, HE4 and
ROMA score interpretation in premenopausal women /
Iva Friščić
The association of concentration of urine
calprotectin with sterile leukocyturia in patients
with bladder cancer / Helena Čičak
14:15 - 15:00
Educational Workshop
From limited sample to reliable results:
practical strategies in allergy testing
Orlando B
14:15 - 15:00
Gabriele Carta,
BIOMEDICA Medizinprodukte GmbH
15:00 - 15:30
Educational Workshop
Next generation hsTnT
Orlando B
15:00 - 15:30
Next generation hsTnT Gen 6: An analytical
evolution and its clinical consequences
Evangelos Giannitsis, Heidelberg, Njemačka
Next generation hsTnT: analytical evaluation
and implementation challenges
Leida Tandara, Split, Croatia
15:30 - 15:45
BREAK
15:45 - 16:15
Educational Workshop
Mindray Hematology Solutions: One tube,
one process, maximum efficiency
Orlando A
15:45 - 16:15
Konstantinos Krontiris, Mindray
16:15 - 16:30
COFFEE BREAK
16:30 - 17:30
Symposium of the Working Group for
Laboratory Endocrinology
National recommendations of the Croatian Society
of Medical Biochemistry and Laboratory Medicine:
Thyroid function tests from the laboratory
point of view
Orlando A
Chair:
Adriana Bokulić
16:30 - 17:30
Adriana Bokulić, Domagoj Marijančević,
Tihana Serdar Hiršl
20:00
CONGRESS DINNER
9:00 - 9:45
Plenary Lecture
Genetics and epigenetics: where are we today
in translational research and clinical application
Orlando A+B
Chair:
Jasenka Wagner Kostadinović
9:00 - 9:45
Daria Pašalić, Zagreb, Croatia
9:45 - 10:00
COFFEE BREAK
10:00 - 12:00
Joint Symposium with Horizon Project
Attract Adria
miRNA in germ cell tumors
Orlando A
Chair:
Ivana Ćelap
10:00 - 10:15
AttractAdria: A new research ecosystem for
personalized preventive healthcare in the
Adria region
Tamer Bego, Sarajevo, Bosnia and Herzegovina
10:15 - 10:40
Germ cell tumors
Monika Ulamec, Zagreb, Croatia
10:40 - 11:05
miRNA-371 in testicular cancer -
a laboratory perspective
Ivana Ćelap, Zagreb, Croatia
11:05 - 11:30
Results of miRNA-371 in patients with
testicular cancer
Leo Dumbović, Zagreb, Croatia
11:30 - 11:55
The role and value of miRNA-371 in patients
with germ cell tumors - an oncologist’s perspective
Marijana Jazvić, Zagreb, Croatia
11:55 - 12:00
Discussion
12:00 - 13:00
Symposium of the Working Group for Tumor Markers
Tumor markers in contemporary oncology:
from laboratory to clinics